Biotechnology and its Application Mock Test-4

Question No:1

The abbreviation ‘B’ in Bt-toxin stands for

[A] Biotechnology
[B] Biotoxin
[C] Bacillus
[D] Toxin released by bacterium

Question No:2

Which of the following is the source of complementary strand in mRNA silencing?

[A] An infection by viruses having RNA genome
[B] Mobile genetic elements (Transposons)
[C] Both
[D] Proteins

Question No:3

Some of the characteristics of Bt-cotton are

[A] Long fibre and resistance of aphids
[B] Maximum yield, long fibre and resistance to bettle pests
[C] High yield and production of toxin protein crystal which kill dipteran pests only.
[D] High yield and resistance to bollworms

Question No:4

How many recombinant therapeutics have been approved for human use the world over?

[A] 10
[B] 20
[C] 30
[D] 90

Question No:5

Which of the following is produced by genetically engineered bacterium?

[A] Tyrosine
[B] Insulin
[C] Glycogen

Question No:6

How many recombinant products are presently being marketed in India?

[A] 10
[B] 20
[C] 12
[D] 30

Question No:7

Which of the following is not used as a bio weapon?

[A] Bacillus anthracis
[B] Botulinum toxin
[C] Bacillus thuringiensis
[D] Small pox

Question No:8

The main challenge for production of insulin using rDNA technique is

[A] Production of A peptide
[B] Production of B peptide
[C] Getting insulin assembled into a mature form
[D] All of the above

Question No:9

Transgenic plants are produced by

[A] Inducing gene mutation
[B] Arresting spindle fibre formation
[C] Deleting sex chromosome
[D] Introducing foreign genes

Question No:10

Peptide A and peptide B is linked by how many disulphide linkages between their proinsulin?

[A] 1
[B] 2
[C] 3
[D] 4

Question No:11

Some of the steps involved in the production of humulin are given below. Choose the correct sequence.
() Purification of humulin
() Extraction of recombinant gene product from E. coli
() Culturing recombinant E. coli in bioreactors
() Introduction of recombinant plasmid into E. coli
() Synthesis of gene for human insulin artificially
() Insertion of human insulin gene into plasmid

[A] 2,1,4,3,5,6
[B] 1,3,5,6,2,4
[C] 5,6,4,3,2,1
[D] 3,5,2,1,6,4

Question No:12

Which American company in prepared humulin?

[A] Eli Lilly
[B] Ranbaxy
[C] Sun-pharma
[D] Glaxosmith

Question No:13

During the process of prohormone ‘proinsulin’ into mature insulin synthesis

[A] C-peptide is added to proinsulin
[B] C-peptide is removed from proinsulin
[C] |3-peptide is added to proinsulin
[D] (3-peptide is removed from proinsulin

Question No:14

Select the true statements from the following.
() Insulin from animal source, may develop allergy in some patients
() C-peptide is not present in mature insulin
() Recombinant therapeutics do not induce unwanted immunological response.
() Insulin can be administered orally to diabetic patients

[A] 1 and 3 only
[B] 1 and 2 only
[C] 3 and 4 only
[D] 1, 2, 3 only

Question No:15

Cancer is generally caused due to activation/conversion of ______ to ______ and/or inactivation of ______.

[A] oncogene, tumour suppressor gene, protooncogene
[B] tumour suppressor gene, oncogene, protooncogene
[C] proto-oncogene, oncogene, tumour-suppressor gene
[D] oncogene, protooncogene, tumour suppressor gene