Question No:1

Increase in a whole set of chromosome in an organism is known as

[A] Polyploidy
[B] Aneuploidy
[C] Trisomy
[D] Tetrasomy



Question No:2

Langdon down describe Down’s syndrome in which year

[A] 1866
[B] 1890
[C] 1852
[D] 1953



Question No:3

Two allelic genes are located on

[A] The same chromosomes
[B] Two homologous chromosomes
[C] Two non-homologous chromosomes
[D] Any two chromosomes



Question No:4

In human beings, the colour of skin is controlled by

[A] Multiple alleles
[B] Lethal genes
[C] Polygenic effect
[D] None of these



Question No:5

Which of the following is genetically dominant in man?

[A] Colour blindness
[B] Rh positive
[C] Haemophilia
[D] Albinism



Question No:6

If a certain patient with blood group B requires immediate blood transfusion, the following type can be given to him

[A] O and B
[B] O and AB
[C] A and AB
[D] Band AB



Question No:7

Karyotype of Klinefelter’s syndrome is

[A] 44+XXY
[B] 44 + XO
[C] 44 + XYY
[D] 44 + XXXY



Question No:8

Which is not a character of Klinefelter’s syndrome?

[A] Masculine development
[B] Gynaecomastia
[C] Fertile individual
[D] Sterile individual



Question No:9

All are characters of Down’s syndrome except

[A] Congenital heart disease
[B] Broad flat face
[C] Small and wrinkled tongue
[D] Many ‘loops’ on finger tips



Question No:10

Which karyotype present monosomy?

[A] 2n+1
[B] 2n-2
[C] 2n-1
[D] 2n + 2



Question No:11

Which karyotype represents trisomy?

[A] 2n+1
[B] 2n-2
[C] 2n – 1
[D] 2n + 2



Question No:12

Find out total number of Mendelian disorder from the following:
Cystic Fibrosis, Haemophilia, Sickle cell anaemia, Colorblindness, Thalesemia, Phenyllketonuria

[A] 4
[B] 5
[C] 6
[D] 3



Question No:13

Which of the following is sex-linked recessive disorder?

[A] Myotonic dystrophy
[B] Sickle-cell anaemia
[C] Haemophilia
[D] Phenylketonuria



Question No:14

Following is autosomal dominant trait

[A] Phenylketonuria
[B] Sickle-cell anaemia
[C] Haemophilia
[D] Myotonic dystrophy



Question No:15

Queen Victoria was a carrier of which disease?

[A] Myotonic dystrophy
[B] Sickle-cell anaemia
[C] Haemophilia
[D] Phenylketonuria