In the context of genetic material, nucleotide consists of
[A] N-base, Ribose sugar, Phosphate group
[B] N-base, Hexose sugar, Phosphate group
[C] Nucleoside + Phosphate
[D] Both (a) and (c)
Uracil is associated with which sugar?
[A] Generally Deoxyribose
[B] Sometimes Ribose
[C] Only ribose
5 – end of ribose sugar bears
[C] Phosphate group
[D] Hydroxyl group
3‘ end of the polynucleotide chain bears
[A] Phosphate group
[B] Hydroxyl group
[C] Methyl group
[D] Nitro group
In RNA, every nucleotide residue has an additional _____ group present at _____ position of ribose
[A] PO43- 3‘
[B] OH – ,3
[C] OH – ,2
Thymine can also be designated as
[A] 3 – Methyl uracil
[B] 2 – Methyl uracil
[C] 4 – Methyl uracil
[D] 5 – Methyl Uracil
J.D. Watson and F.H. Crick utilized X-ray diffraction data produced by
[A] Rosalind Wilkins and Maurice Franklin
[B] Maurice Wilkins and Rosalind Franklin
[C] Sutton and Boveri
[D] None of the above
Erwin Chargaff found that
[A] Ratios of adenine and cytosine and thymine and guanine are constant.
[B] Ratios of adenine and thymine and guanine and cytosine are constant.
[C] Ratios of adenine and guanine and thymine and cytosine are constant.
[D] Ratios of adenine – guanine and thymine – cytosine are constant.
DNA has two strands which are _____ to each other.
The backbone of DNA double helix consists of
[C] Sugar-Hydroxyl group
[D] Sugar-Methyl group
Anti-parallel polarity is exhibited by
Which of the following holds true in case of DNA?
[A] A = T
[B] Adenine forms two H-bond with thymine
[C] Adenine forms one π bond with thymine
[D] Both (a) and (b)
Three H-bonds is exhibited by which DNA bases in double helix structure?
[A] Adenine, Guanine
[B] Guanine, Cytosine
[C] Cytosine; Thymine
[D] Adenine, Thymine
Double helix model of DNA has a pitch of
[A] 0.34 nm
[B] 3.4 nm
[C] 34 Å
[D] Both (b) and (c)
What confers additional stability to double helix model of DNA apart from the H-bond?
[A] One base pair provides inductive effect to the other.
[B] One base pair is stacked over the other.
[C] One base pair is perpendicular to another.
[D] One base pair interacts with another base pair via steric hindrance.