Question No:1

First clinical gene therapy was given to a ______ year old girl,

[A] 2 year
[B] 6 year
[C] 4 year
[D] 8 year



Question No:2

Conventional method of diagnosis involves

[A] Urine analysis
[B] ELISA
[C] PCR
[D] r-DNA technology



Question No:3

PCR used in detection of

[A] HIV(AIDS)
[B] Cancer
[C] Genetic disorder
[D] All of these



Question No:4

When a patient with defective ADA is treated, which of the following steps are performed for gene therapy?
(A) Lymphocytes are obtained from the patients.
(B) Lymphocytes are transferred to culture dishes.
(C) Lymphocytes are transected with normal ADA genes
(D) The transected cells are returned to the patients

[A] All of the above
[B] Only C and D
[C] Only D
[D] SCID cannot be treated



Question No:5

Which of the following is a benefit to having insulin produced by biotechnology?

[A] It is just as effective and is less expensive,
[B] It can be produced in large quantity,
[C] It is non allergic.
[D] All of the above



Question No:6

Which one of the following genes is defective in patients suffering from serve combined immunodeficiency syndrome (SCID)?

[A] RNA ase
[B] ADA
[C] Carbonic anhydrase .
[D] DNA ase



Question No:7

A functional ADA cDNA can be introduced into cells of the patients receiving gene therapy by using vector constituted by

[A] E coli
[B] Reovirus
[C] Retrovirus
[D] Agrobacterium



Question No:8

Which of the following is used as probe?

[A] Single standard DNA
[B] dsDNA tagged with a radioactive molecule
[C] Single standard RNA tagged with a radioactive molecule
[D] dsRNA



Question No:9

Which gene does not appear in photographic film in autoradiography?

[A] Housekeeping gene
[B] Structural gene
[C] Mutated gene
[D] Transcription ally active gene



Question No:10

Which of the following is based on antigen-antibody reaction?

[A] PCR
[B] ELISA
[C] Serum analysis
[D] Southern blotting



Question No:11

Which of the following can be detected in ELISA?

[A] Protein antigen
[B] Glycoprotein antigen
[C] Antibodies synthesized against pathogen
[D] Any of the above



Question No:12

Over % of all existing transgenic animals are

[A] Pig
[B] Mice
[C] Sheep
[D] Cow



Question No:13

Transgenic organisms are used

[A] to study disease
[B] to produce biological product
[C] to test vaccine safety
[D] All of the above